Gout is a disorder caused by hyperuricemia that results in the precipitation of monosodium urate crystals in and around joints, most often causing recurrent acute or chronic arthritis. The initial attack (flare) of gout is usually non-articular and often involves the 1st metatarsophalangeal joint. Symptoms of gout include acute, severe pain, tenderness, warmth, redness, and swelling. Diagnosis requires identification of crystals in synovial fluid. Treatment of acute attacks is with anti-inflammatory drugs. The frequency of attacks can be reduced by regular use of NSAIDs, colchicine, or both and by lowering the serum urate level with allopurinol, febuxostat, or uricosuric drugs such as lesinurad and probenecid.
- Track 1-1 tophaceous gout and pseudogout
- Track 2-2 New Therapeutic Strategies
- Track 3-3 Pathology and Clinical Management
- Track 4-4 Pathology and Clinical Management
- Track 5-5 prevalence, incidence and risk factors